Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0307460
PubChem CID
Molecular Formula
C4H7N3O2
Molecular Weight
129.119 g/mol
Synonyms/Alias
[CHEMBL456781; 5-(2-aminoethyl)-2;3-dihydro-1;3;4-oxadiazol-2-one; CHEMBL1186275; BDBM50273003; AKOS006350447; EN300-7232027; [5-(2-Amino-ethyl)-3H-[1;3;4]oxadiazol-2-one Hydrochloride]
InChI Key
WNSKGEZANNTPQJ-UHFFFAOYSA-N
InChI
InChI=1S/C4H7N3O2/c5-2-1-3-6-7-4(8)9-3/h1-2,5H2,(H,7,8)
IUPAC Name
5-(2-aminoethyl)-3H-1,3,4-oxadiazol-2-one
CAS Number
1235995-16-0

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

16 16 0 0 0 0 0 0 0 0999 V2000
-0.7145 -0.6191 0.2562 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.4975 0.2699 -0.7100 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.9067 -0.109...

Experimental Data

Activity Data

Target Ion Channel
Gamma-aminobutyric acid receptor subunit alpha-6
Uniprot Accession Number
Function
Agonist
Species
Rattus norvegicus (Rat)
IC50
IC50: 7400 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.3
Holding Potential
Not specified
Temperature
Room Temperature
Test Method
Binding assay
Test Species
Not specified

Binding Information

Binding Site
Extracellular domain
Binding Site Residue
GABA Binding Site

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
9
Rotatable Bonds
2
logP
-1.1359
Complexity
29.8821
TPSA (Ų)
84.91
H-Bond Donors
2
H-Bond Acceptors
4
Ring Count
1
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